USC vs. Michigan Prediction: Odds, Picks, Best Bets – September 21, 2024

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A pair of Big Ten teams square off when the No. 11 USC Trojans (2-0) face off against the No. 18 Michigan Wolverines (2-1) on Saturday, September 21, 2024 at Michigan Stadium. The Trojans are favored by 5.5 points. The over/under for the ou🔯ting is 44.5 points.

USC vs. Michigan Favorite, Moneyline, Total

  • Spread favorite: Trojans (-5.5)
  • Moneyline: Trojans (-205), Wolverines (+170)
  • Total: 44.5 points
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    How to Watch USC vs. Michigan

  • When: Saturday, September 21, 2024 at 3:30 p.m. ET
  • Location: Michigan Stadium in Ann Arbor, Michigan
  • TV: CBS
  • Live Stream:
  • Live Stream:
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  • USC 2024 Stats & Rankings

    Stat Average (Total) Rank
    Pass yards 336.5 (673) 8
    Rush yards 159.0 (318) 68
    Points scored 37.5 (75) 81
    Pass yards against 203.5 (407) 68
    Rush yards against 102.0 (204) 33
    Points allowed 10.0 (20) 18

    USC 2024 Betting Info

  • The Trojans have won all two of its games against the spread this season.
  • In games it has played as at least 5.5-point favorites this season, USC is 1-0 against the spread.
  • The average over/under the Trojans have had set in matchups this year is 20.8 more points than this outing’s point total.
  • USC Home/Away Splits (2023)

    Overall Home Away
    Point Total AVG 66.1 64.7 68.4
    Implied Total AVG 41.8 41.1 42.8
    ATS Record 4-9-0 3-5-0 1-4-0
    Over/Under Record 10-3-0 6-2-0 4-1-0
    Moneyline Favorite Record 7-2 4-2 3-0
    Moneyline Underdog Record 1-3 1-1 0-2

    USC’s Offense vs. Michigan’s Defense (2024)

  • The Wolverines’ defense allows 234.3 yards through the air per game (90th in the FBS). The Trojans’ 336.5 passing yards per game is eighth in college football.
  • The Trojans are 35th in the FBS in third-down percentage (47.4%) and will be up against the 100th-ranked Wolverines defense in that category (41.3%).
  • Michigan 2024 Stats & Rankings

    Stat Average (Total) Rank
    Pass yards 153.0 (459) 121
    Rush yards 176.3 (529) 50
    Points scored 23.3 (70) 89
    Pass yards against 234.3 (703) 90
    Rush yards against 70.0 (210) 15
    Points allowed 19.7 (59) 57

    Michigan 2024 Betting Info

  • The Wolverines are winless against the spread this year.
  • USC is 1-0 against the spread so far when playing as at least 5.5-point favorites.
  • One Wolverines game (out of three) has gone over the point total this year.
  • The Trojans’ average total in outings this season has been 65.3, 20.8 points higher than the total in this particular game.
  • Michigan Home/Away Splits (2023)

    Overall Home Away
    Point Total AVG 45.2 45.2
    Implied Total AVG 31.0 31.0
    ATS Record 0-3-0 0-3-0 0-0-0
    Over/Under Record 1-2-0 1-2-0 0-0-0
    Moneyline Favorite Record 2-0 2-0 0-0
    Moneyline Underdog Record 0-1 0-1 0-0

    Michigan’s Offense vs. USC’s Defense (2024)

  • The Wolverines’ offense ranks 99th in the FBS at 23.3 points per game. The Trojans give up 10.0 per game (18th in college football).
  • Michigan’s offense averages 5.9 yards per pass attempt (117th in the FBS). USC’s defense gives up 6.3 yards per passing play (51st in college football).
  • The Wolverines have a 0.4 point-per-play average (76th in the FBS), while the Trojans give up 0.2 per play (15th in college football).
  • Michigan’s 153.0 passing yards per game ranks 121st in the FBS. USC’s defense allows 203.5 through the air (68th in college football).
  • USC vs. Michigan Prediction and Pick

    Our prediction for USC vs💝. Michigan is the Wolv༒erines (+170 on the moneyline) as the pick to win. As for the over/under, we prefer the over at 44.5 points.

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